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2016 03/18

MST1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice. Biochem Biophys Res Commun.

Geng C., Zhang Y., Gao Y., Tao W., Zhang H., Liu X., Fang F.. and Y. Chang
(2016) Biochem Biophys Res Commun. 471:444-9.
2016 02/12

MAZ mediates the cross-talk between CT-1 and NOTCH1 signaling during gliogenesis.

Bin Liu, Anyun Ma, Feng Zhang, Yumeng Wang, Zengmin Li, Qingyu Li, Zhiheng Xu and Yufang Zheng
Scientific Reports. 2016 Feb 12; 6:21534. doi: 10.1038/srep21534.
2015 12/25

Mammalian sterile 20-like kinase 1 (Mst1) enhances the stability of forkhead box P3 (Foxp3) and the function of regulatory T cells by modulating Foxp3 acetylation.

Li C, Shi H, Du X, Deng K, Chi H, Tao W
Journal Of Biological Chemistry 2015 290(52): 30762-770.
2015 11/19

NADP(+)-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance.

Li F, He X, Ye D, Lin Y, Yu H, Yao C, Huang L, Zhang J, Wang F, Xu S, Wu X, Liu L, Yang C, Shi J, He X, Liu J, Qu Y, Guo F, Zhao J, Xu W, Zhao S
Mol Cell. 2015 Nov 19;60(4):661-75. Epub 2015 Nov 19.
2015 06/04

The non-canonical Hippo/Mst pathway in lymphocyte development and functions.

Du X, Yu A, Tao W
2015 47(1): 60-64.
2015 06/01

Leiomodin-3-deficient mice display nemaline myopathy with fast-myofiber atrophy.

Lei Tian, Sheng Ding Yun You Tong-ruei Li Yan Liu, Xiaohui Wu, Ling Sun and Tian Xu
Disease Models & Mechanisms. 2015 Jun 1; 8(6): 635–641. doi: 10.1242/dmm.019430.
2015 03/10

PP6 controls T cell development and homeostasis by negatively regulating distal TCR signaling.

Ye, J., Shi, H., Shen, Y., Li, C., Peng, C., Liu, Y., Deng, K., Geng, JG, Xu, T., Zhuang, Y., Zheng, B and W. Tao
Dev Biol. 2014 Aug 1;392(1):108-16. doi: 10.1016/j. ydbio.2014.04.018. Epub 2014 May 4.
2014 08/10

Phosphorylation of CDK2 at threonine 160 regulates meiotic p achytene and diplotene progression in mice.

Liu W, Wang L, Zhao W, Song G, Xu R, Wang G, Wang F, Li W, Lian J, Tian H, Wang X, Sun F.
Nat Immunol. 2014 Jul;15(7):612-22. do i: 10.1038/ni.2898. Epub 2014 May 25.
2014 07/20

Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO.

Liu J, Han C, Xie B, Wu Y, Liu S, Chen K, Xia M, Zhang Y, Song L, Li Z, Zhang T, Ma F, Wang Q, Wang J, Deng K, Zhuang Y, Wu X, Yu Y, Xu T, Cao X.
Hum Mol Genet. 2014 Jul 15;23(14):3792-800. do i: 10.1093/hmg/ddu092. Epub 2014 Feb 23.
2014 07/15

A piggyBac insertion disrupts Foxl2 expression that mimics B PES syndrome in mice.

Shi F, Ding S, Zhao S, Han M, Zhuang Y, Xu T, Wu X.
Cell Res. 2014 May;24(5):636-9. doi: 10.1038/c r.2014.24. Epub 2014 Feb 25.
2014 05/17

Beadex affects gastric emptying in Drosophila.

Ren J, Zhu H, Chi C, Mehrmohamadi M, Deng K, Wu X, Xu T.
PLos One 9(3): e90701.
2014 03/10

Mst1 and Mst2 are essential regulators of trophoblast differentiation and placenta morphogenesis.

Du, X., Dong, Y., Shi, H., Li, J., Kong, S., Shi, D., Sun, L. V., Deng, K., Xu, T. and W.Tao.
PLoS Genet. 2014 Feb 27;10(2):e1004099. doi: 10.1371/journal.pgen.1004099. eCollection 2014.
2014 02/27

Analysis of meiosis in SUN1 deficient mice reveals a distinct role of SUN2 in mammalian meiotic LINC complex formation and function.

Link J, Leubner M, Schmitt J, Gob E, Benavente R, Jeang KT, Xu R, Alsheimer M.
Journal of Immunology 192 :1525-1535.
2014 02/15

Mst1/Mst2 regulate development and function of regulatory T cells through modulation of Foxo1/Foxo3 stability in autoimmune disease.

Du, X., Shi, H., Li, J., Dong, Y., Liang, J., Ye, J., Kong, S., Zhang, S., Zhong, T., Yuan, Z., Xu, T., Zhuang, Y., Zheng, B., Geng, J. G. and W. Tao.
Immunity. 2013 Sep 19;39(3):470-81. doi: 10.1016/j.immuni.2013.08.016. Epub 2013 Sep 5.
2013 09/19

Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20.

Xia M, Liu J, Wu X, Liu S, Li G, Han C, Song L, Li Z, Wang Q, Wang J, Xu T, Cao X.
Cell Res. 2013 Jul;23(7):972. doi: 10.1038/cr.2013.84.
2013 07/23

Dlic1 deficiency impairs ciliogenesis of photoreceptors by destabilizing dynein.

Kong S, Du X, Peng C, Wu Y, Li H, Jin X, Hou L, Deng K, Xu T, Tao W.
Dis Model Mech. 2013 May;6(3):828-33. doi: 10.1242/dmm.010827. Epub 2013 Mar 8.
2013 05/06

piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice.

Li R, Zhuang Y, Han M, Xu T, Wu X.
Curr Biol. 2012 Sep 11;22(17):1609-15. doi: 10.1016/j.cub.2012.06.043. Epub 2012 Aug 2.
2012 11/11

Inner nuclear envelope proteins SUN1 and SUN2 play a prominent role in the DNA damage response.

Lei K, Zhu X, Xu R, Shao C, Xu T, Zhuang Y, Han M.
J Biol Chem. 2012 Sep 21;287(39):32861-73. Epub 2012 Aug 1.
2012 09/21

Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.

Peng C, Ye J, Yan S, Kong S, Shen Y, Li C, Li Q, Zheng Y, Deng K, Xu T, Tao W.
J Cell Biol. 2012 Jul 23;198(2):165-72. doi: 10.1083/jcb.201204085.

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