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2019 03/31

Gen1 modulates metanephric morphology through retinoic acid signaling

Zhang Y, Zhang X, Wang X, Wang H, Wu X, Xu H*, Shen Q*
DNA and Cell Biology; 2019 Mar;38(3):263-271
2019 02/28

The rare mutation in the endosome-associated recycling protein gene VPS50 is associated with human neural tube defects

Shi Z, Chen S, Han X, Peng R, Luo J, Yang L, Zheng Y*, Wang H*
Molecular Cytogenetics; 2019 Feb; 12: 8
2019 01/22

Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling.

Xie Y, Ma A, Wang B, Peng R, Jing Y, Wang D, Finnell RH., Qiao B, Wang Y*, Wang H*, Zheng Y*.
Clin Sci (Lond). 2019 Jan 22;133(2):225-238. doi: 10.1042/CS20180842.
2018 11/20

Hippo kinases Mst1 and Mst2 sense and amplify IL-2R−STAT5 signaling in Treg cells to establish stable regulatory activity.

Shi H. Liu C, Tan H, Li Y, Nguyen TL, Dhungana Y, Guy C, Vogel P, Neale G, Rankin S, Feng Y, Peng J, Tao W*, Chi H.
Immunity. 2018 Nov 20;49(5):899. doi: 10.1016/j.immuni.2018.10.010.
2018 10/10

TBX6 compound inheritance leads to congenital vertebral malformations in humans and mice.

Yang N, Wu N, Zhang L, Zhao Y, Liu J, Liang X, Ren X, Li W, Chen W, Dong S, Zhao S, Lin J, Xiang H, Xue H, Chen L, Sun H, Zhang J, Shi J, Zhang S, Lu D, Wu X*, Jin L, Ding J, Qiu G, Wu Z, Lupski JR, Zhang F.
Hum Mol Genet. 2018 Oct 10.
2018 07/05

Threshold for neural tube defect risk by accumulated singleton loss-of-function variants.

Chen Z, Lei Y, Zheng Y, Aguiar-Pulido V, Ross M.E., Peng R, Jin L, Zhang T*, Finnell R.H.,*, Wang H*
Cell Research. 2018 Jul 5; doi: 10.1038/s41422-018-0061-3.
2018 07/02

The Vitamin K Epoxide Reductase Vkorc1l1 Promotes Preadipocyte Differentiation in Mice.

Ding Yi， Cui J， Wang Q， Shen SQ， Xu T， Tang HR， Han M， Wu X*
Obesity. 2018 Jul 2; doi: 10.1002/oby.22206.
2018 05/06

Network correlation analysis revealed potential new mechanisms for neural tube defects beyond folic acid.

Gao X, Finnell R, Wang H, Zheng Y*
Birth Defects Res A. 2018 May 6. doi: 10.1002/bdr2.1336.
2018 05/03

Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice.

Wang B, Zhang Y, Dong H, Gong S, Wei B, Luo M, Wang H, Wu X, Liu W, Xu X*, Zheng Y*, Miao Sun*
Cell Death Dis. 2018 May 3; 9(5):520. doi: 10.1038/s41419-018-0563-4.
2018 05/01

Formate Rescues Neural Tube Defects Caused by Mutations in Slc25a32.

Kim J, Lei Y, Guo J, Kim S, Wlodarczyk B, Robert M. Cabrera RM, Lin Y, Nilsson T, Zhang T, Ren A, Wang L, Yuan Z, Zheng Y, Wang H*, Finnell RH.*
PNAS, 2018 May 1;115(18):4690-4695. doi: 10.1073/pnas.1800138115.
2018 04/04

Genetic analysis of Wnt/PCP genes in neural tube defects.

Chen Z, Lei Y, Cao X, Zheng Y, Wang F, Bao Y, Peng R, Finnell RH*, Zhang T*, Wang H*
BMC Med Genomics. 2018 Apr 4; 11(1): 38. doi: 10.1186/s12920-018-0355-9.
2018 03/28

Decreased activity of RCAN1.4 is a potential risk factor for congenital heart disease in a Han Chinese population.

Cheng LP, Li PQ, Wang H, Yang XY, Zhou HM, Tao W*, Tian J*, Wang H*
Protein & Cell. 2018 Mar 28. doi: 10.1007/s13238-018-0525-8.
2018 01/09

Sensing and transmitting intracellular amino acid signals through reversible lysine aminoacylations.

He XD, Gong W, Zhang JN, Nie J, Yao CF, Guo FS, Lin Y, Wu XH, Li F, Li J, Sun WC, Wang ED, An YP, Tang HR, Yan GQ, Yang PY, Wei Y, Mao YZ, Lin PC, Zhao JY, Xu YH*, Xu W*, Zhao SM*
Cell metabolism. 2018 Jan 9;27(1),151-166. doi: 10.1016/j.cmet.2017.10.015.
2018 01/01

Disruption of Gen1 Causes Congenital Anomalies of the Kidney and Urinary Tract in Mice.

Wang HR, Zhang C, Wang XW, Lian YR, Guo B, Han M, Zhang XE, Zhu XT, Xu SX, Guo ZL, Bi YL, Shen Q, Wang X, Liu JJ, Zhuang Y, Ni T, Xu H*, Wu X*
Int J Biol Sci. 2018 Jan 1; 14(1): 10-20. doi: 10.7150/ijbs.22768.
2017 11/10

Hdac7 promotes lung tumorigenesis by inhibiting Stat3 activation.

Lei Y., Liu L., Zhang S., Shicheng Guo S., Li X., Wang J., Bo Su B., Fang Y., Chen X, Ke H. and W. Tao*
Molecular Cancer. 2017 Nov 10;16:170. DOI 10.1186/s12943-017-0736-2.
2017 09/29

Novel mutation of LRP6 identified in Chinese Han population links canonical WNT signaling to neural tube defects.

Shi Z, Yang X, Li B, Chen S, Yang L, Chen L, Zhang T, Wang H, Zheng Y*
Birth Defects Res A. 2017 Sep 29. doi: 10.1002/bdr2.1122.
2017 09/19

Mst-1 deficiency promotes post-traumatic spinal motor neuron survival via enhancement of autophagy flux.

Zhang M., Tao W., Yuan Z. and Y. Liu
J. Neurochem. 2017 Sep 19;2143(2):244-256.
2017 06/19

A missense mutation in TCN2 is associated with decreased risk for congenital heart defects and may increase cellular uptake of vitamin B12 via Megalin.

Li P, Huang L, Zheng Y, Pan X, Peng R, Jiang Y, Finnell RH, Li H, Qiao B, Wang HY*
Oncotarget. 2017 July 19;8(33):55216-55229. doi: 10.18632/oncotarget.19377.
2017 06/11

DNA-PK facilitates piggyBac transposition by promoting paired-end complex formation.

Jin Y, Chen YH, Zhao SM, Guan KL, Zhuang Y, Zhou WH, Wu X*, Xu T*
PNAS. 2017 Jul 11;114(28):7408-7413.

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