MORE研究所科研动态

2021 12/08

Disruption of Gen1 Causes Ectopic Budding and Kidney Hypoplasia in Mice
Congenital anomalies of the kidney and urinary tract (CAKUT) are a family of often-concurrent diseaseswith various anatomical spectra. Null-mutantGen1mice frequently develop multiple urinary pheno-types, most commonly...【详细】
2021 10/25

MeCP2 duplication causes hyperandrogenism by upregulating LHCGR and downregulating RORα
Duplication ofMECP2(methyl-CpG-binding protein 2) gene causes a serious neurological and developmental disorder calledMECP2duplication syndrome (MDS), which is usually found in males...【详细】
2021 07/30

The chemerin-CMKLR1 axis limits thermogenesis by controlling a beige adipocyte/IL-33/type 2 innate immunity circuit
IL-33-associated type 2 innate immunity has been shown to support beige fat formation and thermogenesis in subcutaneous inguinal white adipose tissue (iWAT), but little is known about how it is regulated...【详细】
2021 04/30

Organoids as a new model system to study neural tube defects
The neural tube is the first critically important structure that develops in the embryo. It serves as the primordium of the central nervous system; therefore, the proper for-mation of the neural tube is essential to the developing...【详细】
2021 04/22

Codonopsis Radix modulates water and electrolytes homeostasis in mice
Codonopsis Radix is a traditional Chinese medicine best known for its effects in treating digestive, cardiovascular,immunological and hematopoitic diseases. It also appears in the traditional Chinese...【详细】