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郑煜芳 博士

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    1997年获清华大学生物科学与技术学士学位,1999年获清华大学生物物理硕士学位。2004年获美国康奈尔大学医学院生理和生物物理博士学位。2004-2007年在美国耶鲁大学从事博士后研究。2007年11月任复旦大学生命科学学院副教授。

     

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    主要研究大脑皮层发育过程中的神经元细胞的迁移和导向的调控以及神经元细胞和胶质细胞之间的相互作用对于大脑发育和衰老的作用,并探讨相关神经发育障碍疾病的机制。

     

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    2012年 复旦大学卓学计划

    2012年 复旦大学生命科学学院 复星奖教金个人奖

    2010年 复旦大学生命科学学院 复星奖教金个人奖

    2008年 上海市浦江人才计划,2010年结题获评优秀

     

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    1.Xiaojin Qiao#, Yahui Liu#, Peiqiang Li, Zhongzhong Chen, Huili Li, Xueyan Yang, Richard H. Finnell, Zhangmin Yang, Ting Zhang, Bin Qiao, Yufang Zheng*, Hongyan Wang*. Genetic analysis of rare coding mutations in CELSR1-3 in Chinese Congenital Heart and Neural Tube Defects. Clin Sci (Lond). 2016 Oct 18. 130(24): 2329-40, doi: 10.1042/CS20160686.

    2.Wang B#, Zheng Y#, Shi H, Du X, Zhang Y, Wei B, Luo M, Wang H, Wu X, Hua X, Sun M*, Xu X*. Zfp462 deficiency causes anxiety-like behaviors with excessive self-grooming in mice. Genes Brain Behav. 2016 Sep 13. doi: 10.1111/gbb.12339.

    3.Yu LW, Wang F, Yang XY, Sun SN, Zheng YF, Li BB, Gui YH, Wang HY. Mild decrease in TBX20 promoter activity is a potentially protective factor against congenital heart defects in the Han Chinese population. Scientific Reports, 2016 Apr 1;6:23662. doi: 10.1038/srep23662.

    4. Bin Liu, Anyun Ma, Feng Zhang, Yumeng Wang, Zengmin Li, Qingyu Li, Zhiheng Xu and Yufang Zheng*(2016).MAZ mediates the cross-talk between CT-1 and NOTCH1 signaling during gliogenesis.Scientific Reports. 6:21534.

    5. Qingyu Li, Bin Liu, Zhengyu Zhang, Mei Zhou, Le Pan, Zhixing Ma, Zengmin Li, Yufang Zheng*(2013).ADAM17 is critical for multipolar exit and radial migration of neuronal intermediate progenitor cells in mice cerebral cortex. PLoS One (accepted)

    6. Zhixing Ma, Qingyu Li, Zhengyu Zhang, Yufang Zheng*. A Disintegrin and Metalloprotease 10 in neuronal maturation and gliogenesis during cortex development. Neural Regen Res. 2013, 8(1):24-30

    7. Peng C, Ye J, Yan S, Kong S, Shen Y, Li C, Li Q, Zheng Y, Deng K, Xu T, Tao W. Ablation of vacuole protein sorting 18 (vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes. J Biol Chem. 2012 Sep 21;287(39):32861-73.

    8. Juan Li, Bin Liu, Xiaofei Gao, Zhixing Ma, Tianyi CaoSong, Yan-ai Mei, Yufang Zheng*. Overexpression of Sigma-1 receptor inhibits ADAM10 and ADAM17 mediated shedding in vitro. Protein Cell 2012 Feb; 3(2): 153-9.

    9. Ly A, Nikolaev A, Suresh G, Zheng Y, Tessier-Lavigne M, Stein E. DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell (pISSN: 0092-8674) 2008 Jun 27; 133: 1241-1254